Nmda receptors and huntingtons disease biology of the. Neurobiology of huntingtons disease ncbi bookshelf. It should be useful as a revision guide or to find. Weve a huge range of the best used biology and life science books at cheap prices with free uk delivery from animals and humans to marine biology books. Which symptoms appear first varies greatly from person to person. Advanced science for a level biology, chemistry and physics. Huntington s disease has a broad impact on a persons functional abilities and usually results in movement, thinking cognitive and psychiatric disorders. Drawing on the expertise of key researchers in the field, the book discusses the basic neurobiology of huntingtons disease. Free concepts of biology book available for download openstax.
Students will find that this textbook offers a strong introduction to human. This genetic, autosomaldominant disease is caused by a mutation in exon 1 of the it15 gene, resulting in the expansion of a cag repeat encoding a polyglutamine polyq region near the nterminus of the huntingtin protein. The molecular biology of huntington s disease, including new chapters on the normal function of huntingtin, the molecular pathogenesis of huntington s disease and the peripheral pathology of the disorder, and an extensively updated chapter on its structural biology. Huntington s disease is an inherited disease that causes the progressive breakdown degeneration of nerve cells in the brain. Study biology online for free by downloading openstaxs college biology 2e book and using our accompanying online resources including a. The death of the genetic theory of disease transmission. Buy head start to alevel biology cgp alevel biology by cgp books isbn. Free biology 2e textbook available for download openstax. Rubinsztein skip to main content accessibility help we use cookies to distinguish you from other users and to provide you with a better experience on our websites. The molecular biology of huntington s disease volume 31 issue 1 l. Alevel biology wikibooks, open books for an open world.
Study biology online free by downloading openstaxs concepts of biology book and using our accompanying online resources including a biology study guide. Ocr level 3 advanced gce in biology a h420 specification. Human health and disease jump to navigation jump to search an infectious disease is a disease resulting from the presence of pathogens including viruses, bacteria, fungi, protozoa and multicellular parasites. This book is based on the ocr and aqa alevel biology specifications, but is not endorsed by either exam board.
Any textbooks endorsed to support the syllabus for examination from 2016 are still suitable for use with this. Nessa careys book combines an easy style with a textbooks thoroughness. Human biology open textbook library center for open education. Huntingtons disease hd is an inherited, progressive neurodegenerative disorder, with a prevalence of 5 to 10 per 100,000 people. Inside the obriens by lisa genova, eternal on the water by joseph monninger, you me everything by catherine isaac. Even if you dont want to study biology further, the grades you get now will open doors in the future. These classic science textbooks provide support for a level biology, chemistry and physics, whichever specification youre following.
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